Current evaluation and impact of health care on health outcomes via the Internet is limited in its scope in terms of feedback and interaction between the Web, health-care providers, and patients.

A Health Web Observatory underpinned by the academic disciplines of Health Web Science and Medicine 2.0. may provide the infrastructure to address these limitations. Furthermore, a formula is described to consider the effect of digital interventions from the perspective of either the citizen, health professional/policy maker or at the population level. This chapter develops these concepts with exemplars and challenge the Web Science and Medicine 2.0 communities to develop new tools to enable the triangulation of data to understand end-user interaction with the Web and thus identify new integrated strategies for preferable health outcomes.